Measuring Alcohol and Stress Interactions with Structural and Perfusion MRI R01-AA016748
The goal of this collaboration between the NCIGT and Wake Forest University is to develop an adaptive brain perfusion imaging system enabled by real-time updates of PASL acquisitions with the qualities of reference-free Nyquist ghost correction, low latency geometric distortion correction, and an adjustable acquisition plane on-the-fly. The collaboration will accelerate the development process of perfusion imaging projects at Wake Forest. To date, Wake Forest has benefited by having external expertise in image reconstruction methods. In turn, the NCIGT has received guidance about the technical needs in perfusion imaging that has led to novel developments in real-time EPI imaging applicable to a variety of image guided therapy applications. In 2009, researchers jointly presented a novel technique (developed in 2008) to eliminate Nyquist ghosts in EPI at the 2009 ISMRM and ISBI.
Publications
- Hoge WS, Tan H, Kraft RA, A Method for Continuous Accelerated Echo-Planar Imaging with Self-Referenced Parallel MR Reconstruction and Artifact Correction, ISBI 2009.
- Hoge WS, Tan H, Kraft RA, Improved Self-Referenced Parallel MRI imaging in EPI by using UNFOLD to Remove Nyquist Ghosts, ISMRM 2009. pp. 2720.
- Hoge WS, Tan H, Kraft RA. Improved PASL EPI acquisitions with parallel imaging and UNFOLD. Proceedings of the 42nd Annual IEEE Asilomar Conf. on Signals, Systems, and Computers 2008.